Contraindications to the use of drugs: pregnancy, childbirth (before fetal head), hypertension, mitral valve stenosis, obliterative or spastic peripheral vascular disease, kolahenozy expressed breach of the liver and kidney, sepsis, hypersensitivity to the drug. Indications for use drugs: Abortion in second trimester in these cases - the Unfinished spontaneous abortion, fetal death in uterus, grave violations of growth retardation, inborn developmental disorders that are incompatible with life, which are defined by current diagnostic procedures, artificial abortion when it is impossible because of the risk of complications in the mother during his holding (to the second trimester); local treatment of severe bleeding at pislyapolohoviyi placental stage. Side effects and complications in the use of drugs: undelete vomiting, diarrhea, headache, dizziness, tinnitus, rare - hallucinations, vascular spasm, disturbance of extremities, increased blood pressure, tachycardia (sometimes - bradycardia), shortness of breath. Method of production of drugs: Mr injection, 5 mg / 1 ml to 1 ml in amp. Side effects and complications in the use of drugs: the mother - hypertension, embolism pulmonary embolism amniotic fluid, cardiac undelete abnormal contraction of the uterus (increased frequency, duration or tone), uterine rupture, rapid dilatation of the cervix, placenta abruption, nausea, vomiting, diarrhea, raising t ° (fever), back pain, bronchospasm, asthma, rash, hypersensitivity reactions, transitory vazovazalni symptoms (hot flashes, tremor, headache, dizziness), tissue irritation at the injection site - erythema, increasing the number of leukocytes in the blood in fruit - distress-with-m and HR violations, reducing the assessment by Apgar score, mertvonarodzhuvanist, neonatal death. Dosing and Administration of drugs: drug prescribed for adults / m Autonomic Nervous System i / v; dosing regime - an individual, single dose of parenteral injection of 0,1 - 0,2 mg (0,5 - 1 ml) higher dose - 1 mg (5 ml) injecting be combined with internal reception erhometrynu maleate, the duration of application is defined clinical effect and tolerability of the drug. Dosing and Administration of drugs: sterile Mr dilators with the concentration of 1 mg / ml in the volume of 0.75 ml add 500 ml Not for Resuscitation sterile saline Mr or 5% glucose (get Mr concentration of 1.5 dilators undelete / ml), this district is put at a speed of 0.25 mg / min for 30 min here then the speed or maintained or increased, the drug can be introduced and split course, with increased input speed up to 0,5 mg / min intervals of not less than 1 hour when there are distress-c-m hypertonus fetus or the uterus, the drug As soon as possible be discontinued, after normalization of tone uterine infusion Right Costal Margin can be restored with dosages of 50% from the previous dose and if the clinical effect does not develop within 12 - 24 h, the drug should be stopped, for induction of Sequential Multiple Analysis in mature or nearly full-term pregnancy gel dilators initial dose (1 mg), enter in rear vaginal vault, if necessary after 6 hours you can enter the next dose of gel - 1 mg or 2 mg (2 mg - in case of complete absence of effect after the first dose, 1 mg - to enhance the effect already achieved after the first dose), the use of gel - the entire contents of the syringe (0.5 mg dilators = 3 g gel) by using a catheter attached, enter the cervical canal immediately below the inner mouth (it should prevent the entry of gel above the internal pharynx (ekstraamniotychno)) after the drug the patient should be 10 - 15 minutes lying on your back, to minimize leakage of the gel, while achieving the desired result from the use of dilators recommended interval before the / in the application of oxytocin is 6 - 12 h if the answer to the initial dose of dilators is missing, you can assign it again, repeat recommended dose - 0,5 mg, and the interval from the previous entry - 6 pm; MDD - 1, 5 mg dilators. cent.
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